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Machine learning reveals hidden stability code in protein native fluorescence
Conformational stability of a protein is usually obtained by spectroscopically measuring the unfolding melting temperature. However, optical spectra under native conditions are considered to contain too little resolution to probe protein stability. Here, we have built and trained a neural network mo...
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| Publicado no: | Comput Struct Biotechnol J |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Research Network of Computational and Structural Biotechnology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8131987/ https://ncbi.nlm.nih.gov/pubmed/34093990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.047 |
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