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Stereoelectronic effects impact glycan recognition

Recognition of distinct glycans is central to biology, and lectins mediate this function. Lectin glycan preferences are usually centered on specific monosaccharides. In contrast, human intelectin-1 (hItln-1, also known as Omentin-1) is a soluble lectin that binds a range of microbial sugars, includi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: McMahon, Caitlin M., Isabella, Christine R., Windsor, Ian W., Kosma, Paul, Raines, Ronald T., Kiessling, Laura L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392083/
https://ncbi.nlm.nih.gov/pubmed/31930911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b11699
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