Oncogenic KIT modulates type I interferon–mediated antitumor immunity in GIST

Type I interferons (IFN) are implicated in tumor immunogenicity and response to systemic therapy, but their interaction with oncogene signaling is not well understood. Here, we studied oncogenic KIT, which drives gastrointestinal stromal tumor (GIST), the most common sarcoma. Using mouse models of G...

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Bibliografske podrobnosti
izdano v:Cancer Immunol Res
Main Authors: Liu, Mengyuan, Etherington, Mark S., Hanna, Andrew, Medina, Benjamin D., Vitiello, Gerardo A., Bowler, Timothy G., Param, Nesteene J., Levin, Lillian, Rossi, Ferdinand, DeMatteo, Ronald P.
Format: Artigo
Jezik:Inglês
Izdano: 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102332/
https://ncbi.nlm.nih.gov/pubmed/33648985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-20-0692
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