Differential immune profiles distinguish the mutational subtypes of gastrointestinal stromal tumor

Gastrointestinal stromal tumor (GIST) is the most common human sarcoma, frequently characterized by an oncogenic mutation in the KIT or PDGFRA gene. We performed RNA sequencing of 75 human GIST tumors from 75 patients, comprising what we believe to be the largest cohort of GISTs sequenced to date, i...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Vitiello, Gerardo A., Bowler, Timothy G., Liu, Mengyuan, Medina, Benjamin D., Zhang, Jennifer Q., Param, Nesteene J., Loo, Jennifer K., Goldfeder, Rachel L., Chibon, Frederic, Rossi, Ferdinand, Zeng, Shan, DeMatteo, Ronald P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486334/
https://ncbi.nlm.nih.gov/pubmed/30762585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124108
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