Oncogenic KIT modulates type I interferon–mediated antitumor immunity in GIST

Type I interferons (IFN) are implicated in tumor immunogenicity and response to systemic therapy, but their interaction with oncogene signaling is not well understood. Here, we studied oncogenic KIT, which drives gastrointestinal stromal tumor (GIST), the most common sarcoma. Using mouse models of G...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Liu, Mengyuan, Etherington, Mark S., Hanna, Andrew, Medina, Benjamin D., Vitiello, Gerardo A., Bowler, Timothy G., Param, Nesteene J., Levin, Lillian, Rossi, Ferdinand, DeMatteo, Ronald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102332/
https://ncbi.nlm.nih.gov/pubmed/33648985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-20-0692
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