Macrophages and CD8(+) T cells mediate the antitumor efficacy of combined CD40 ligation and imatinib therapy in gastrointestinal stromal tumors

Tyrosine kinase inhibition of gastrointestinal stromal tumors (GIST) is effective but typically culminates in resistance and is rarely curative. Immunotherapy has potential application to GIST, as we previously showed that T-cell checkpoint blockade increases the antitumor effects of imatinib. Here,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Zhang, Jennifer Q., Zeng, Shan, Vitiello, Gerardo A., Seifert, Adrian M., Medina, Benjamin D., Beckman, Michael J., Loo, Jennifer K., Santamaria-Barria, Juan, Maltbaek, Joanna H., Param, Nesteene J., Moral, John A., Zhao, Julia N., Balachandran, Vinod, Rossi, Ferdinand, Antonescu, Cristina R., DeMatteo, Ronald P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203303/
https://ncbi.nlm.nih.gov/pubmed/29467128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0345
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados