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Anti-tumor activity of NLG207 (formerly CRLX101) in combination with enzalutamide in preclinical prostate cancer models

Effective treatments for patients with mCRPC following disease progression on enzalutamide is currently an unmet clinical need. Simultaneous inhibition of the HIF-1α and AR pathways has been shown to overcome enzalutamide resistance in vitro. Combination treatment with NLG207, a nanoparticle-drug co...

詳細記述

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書誌詳細
出版年:Mol Cancer Ther
主要な著者: Schmidt, Keith T., Chau, Cindy H., Strope, Jonathan D., Huitema, Alwin D. R., Sissung, Tristan M., Price, Douglas K., Figg, William D.
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102325/
https://ncbi.nlm.nih.gov/pubmed/33632874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0228
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