Preclinical effects of CRLX101, an investigational camptothecin-containing nanoparticle drug conjugate, on treating glioblastoma multiforme via apoptosis and antiangiogenesis

Malignant gliomas are difficult to treat in clinical practice. This study was aimed to investigate the preclinical efficacy of CRLX101, an investigational nanoparticle-drug conjugate developed by conjugating camptothecin (CPT) with cyclodextrin-polyethylene glycol, against gliomas. CPT fluorescence...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Lin, Chien-Ju, Lin, Yi-Ling, Luh, Frank, Yen, Yun, Chen, Ruei-Ming
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173144/
https://ncbi.nlm.nih.gov/pubmed/27285755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9878
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