Targeting p300/CBP in lethal prostate cancer

Resistance to androgen receptor (AR) blockade in castration resistant prostate cancer (CRPC) is associated with sustained AR signaling, including through alternative splicing of the AR (AR-SV). Inhibitors of transcriptional co-activators that regulate AR activity, including the paralogue histone-ace...

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Publicado no:Cancer Discov
Main Authors: Welti, Jonathan, Sharp, Adam, Brooks, Nigel, Yuan, Wei, McNair, Christopher, Chand, Saswati N., Pal, Abhijit, Figueiredo, Ines, Riisnaes, Ruth, Gurel, Bora, Rekowski, Jan, Bogdan, Denisa, West, William, Young, Barbara, Raja, Meera, Prosser, Amy, Lane, Jordan, Thomson, Stuart, Worthington, Jenny, Onions, Stuart, Shannon, Jonathan, Paoletta, Silvia, Brown, Richard, Smyth, Don, Harbottle, Gareth W., Gil, Veronica S., Miranda, Susana, Crespo, Mateus, Ferreira, Ana, Pereira, Rita, Tunariu, Nina, Carreira, Suzanne, Neeb, Antje J., Ning, Jian, Swain, Amanda, Taddei, David, Schiewer, Matthew J., Knudsen, Karen E., Pegg, Neil, de Bono, Johann S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102310/
https://ncbi.nlm.nih.gov/pubmed/33431496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0751
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