Targeting p300/CBP in lethal prostate cancer

Resistance to androgen receptor (AR) blockade in castration resistant prostate cancer (CRPC) is associated with sustained AR signaling, including through alternative splicing of the AR (AR-SV). Inhibitors of transcriptional co-activators that regulate AR activity, including the paralogue histone-ace...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Discov
Prif Awduron: Welti, Jonathan, Sharp, Adam, Brooks, Nigel, Yuan, Wei, McNair, Christopher, Chand, Saswati N., Pal, Abhijit, Figueiredo, Ines, Riisnaes, Ruth, Gurel, Bora, Rekowski, Jan, Bogdan, Denisa, West, William, Young, Barbara, Raja, Meera, Prosser, Amy, Lane, Jordan, Thomson, Stuart, Worthington, Jenny, Onions, Stuart, Shannon, Jonathan, Paoletta, Silvia, Brown, Richard, Smyth, Don, Harbottle, Gareth W., Gil, Veronica S., Miranda, Susana, Crespo, Mateus, Ferreira, Ana, Pereira, Rita, Tunariu, Nina, Carreira, Suzanne, Neeb, Antje J., Ning, Jian, Swain, Amanda, Taddei, David, Schiewer, Matthew J., Knudsen, Karen E., Pegg, Neil, de Bono, Johann S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102310/
https://ncbi.nlm.nih.gov/pubmed/33431496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0751
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