DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy

The transmembrane Hsp40 DNAJB12 and cytosolic Hsp70 cooperate on the endoplasmic reticulum’s (ER) cytoplasmic face to facilitate the triage of nascent polytopic membrane proteins for folding versus degradation. N1303K is a common mutation that causes misfolding of the ion channel CFTR, but unlike F5...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Biol Cell
Asıl Yazarlar: He, Lihua, Kennedy, Andrew S., Houck, Scott, Aleksandrov, Andrei, Quinney, Nancy L., Cyr-Scully, Alexandra, Cholon, Deborah M., Gentzsch, Martina, Randell, Scott H., Ren, Hong Yu, Cyr, Douglas M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2021
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101465/
https://ncbi.nlm.nih.gov/pubmed/33534640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-11-0688
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller