DNAJB12 and Hsp70 triage arrested intermediates of N1303K-CFTR for endoplasmic reticulum-associated autophagy

The transmembrane Hsp40 DNAJB12 and cytosolic Hsp70 cooperate on the endoplasmic reticulum’s (ER) cytoplasmic face to facilitate the triage of nascent polytopic membrane proteins for folding versus degradation. N1303K is a common mutation that causes misfolding of the ion channel CFTR, but unlike F5...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: He, Lihua, Kennedy, Andrew S., Houck, Scott, Aleksandrov, Andrei, Quinney, Nancy L., Cyr-Scully, Alexandra, Cholon, Deborah M., Gentzsch, Martina, Randell, Scott H., Ren, Hong Yu, Cyr, Douglas M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2021
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101465/
https://ncbi.nlm.nih.gov/pubmed/33534640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-11-0688
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados