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Mechanisms of CFTR Folding at the Endoplasmic Reticulum

In the past decade much has been learned about how Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) folds and misfolds as the etiologic cause of cystic fibrosis (CF). CFTR folding is complex and hierarchical, takes place in multiple cellular compartments and physical environments, and invo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Soo Jung, Skach, William R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521238/
https://ncbi.nlm.nih.gov/pubmed/23248597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00201
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