Alternative splicing perturbation landscape identifies RNA binding proteins as potential therapeutic targets in cancer

Alternative splicing (AS) plays an important role in gene regulation, and AS perturbations are frequently observed in cancer. RNA binding protein (RBP) is one of the molecular determinants of AS, and perturbations in RBP-gene network activity are causally associated with cancer development. Here, we...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Li, Junyi, Pan, Tao, Chen, Liuxin, Wang, Qi, Chang, Zhenghong, Zhou, Weiwei, Li, Xinhui, Xu, Gang, Li, Xia, Li, Yongsheng, Zhang, Yunpeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2021
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099609/
https://ncbi.nlm.nih.gov/pubmed/33996260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.04.005
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