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Alternative splicing perturbation landscape identifies RNA binding proteins as potential therapeutic targets in cancer

Alternative splicing (AS) plays an important role in gene regulation, and AS perturbations are frequently observed in cancer. RNA binding protein (RBP) is one of the molecular determinants of AS, and perturbations in RBP-gene network activity are causally associated with cancer development. Here, we...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther Nucleic Acids
Päätekijät: Li, Junyi, Pan, Tao, Chen, Liuxin, Wang, Qi, Chang, Zhenghong, Zhou, Weiwei, Li, Xinhui, Xu, Gang, Li, Xia, Li, Yongsheng, Zhang, Yunpeng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Gene & Cell Therapy 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099609/
https://ncbi.nlm.nih.gov/pubmed/33996260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.04.005
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