Alternative splicing perturbation landscape identifies RNA binding proteins as potential therapeutic targets in cancer

Alternative splicing (AS) plays an important role in gene regulation, and AS perturbations are frequently observed in cancer. RNA binding protein (RBP) is one of the molecular determinants of AS, and perturbations in RBP-gene network activity are causally associated with cancer development. Here, we...

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Publicat a:Mol Ther Nucleic Acids
Autors principals: Li, Junyi, Pan, Tao, Chen, Liuxin, Wang, Qi, Chang, Zhenghong, Zhou, Weiwei, Li, Xinhui, Xu, Gang, Li, Xia, Li, Yongsheng, Zhang, Yunpeng
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2021
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099609/
https://ncbi.nlm.nih.gov/pubmed/33996260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.04.005
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