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Frequent Co‐Alterations of TP53, p16/CDKN2A, p14 (ARF), PTEN Tumor Suppressor Genes in Human Glioma Cell Lines.

In this study we established the simultaneous status of TP53, p16, p14 (ARF) and PTEN tumor suppressor genes in 34 randomly chosen human glioma cell lines. Nine cell lines (26.4%) harbored mutations or deletions in all four tumor suppressor genes and 22 cell lines (64%) had alterations in at least t...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Ishii, Nobuaki, Maier, Daniel, Merlo, Adrian, Tada, Mitsuhiro, Sawamura, Yutaka, Diserens, Annie‐Claire, Van Meir, Erwin G.
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098486/
https://ncbi.nlm.nih.gov/pubmed/10416987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1999.tb00536.x
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