p73 is not Mutated in Meningiomas as Determined with a Functional Yeast Assay but p73 Expression Increases with Tumor Grade

The p53 gene is normally wild type in meningiomas. Since all three members of the p53 gene family recognize the same DNA sequence, tumors containing wild type p53 could decrease transactivation of p53 target genes by mutating either p63 or p73. In meningiomas the most likely target is p73, because l...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Nozaki, Michimasa, Tada, Mitsuhiro, Kashiwazaki, Haruhiko, Hamou, Marie‐France, Diserens, Annie‐Claire, Shinohe, Yumiko, Sawamura, Yutaka, Iwasaki, Yoshinobu, de Tribolet, Nicolas, Hegi, Monika E.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098457/
https://ncbi.nlm.nih.gov/pubmed/11414472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2001.tb00400.x
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