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PTEN regulation by Akt–EGR1–ARF–PTEN axis
The PTEN tumour suppressor gene is induced by the early growth response 1 (EGR1) transcription factor, which also transactivates p53, p73, and p300/CBP as well as other proapoptotic and anti-cancer genes. Here, we describe a novel Akt–EGR1–alternate reading frame (ARF)–PTEN axis, in which PTEN activ...
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| Hlavní autoři: | , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633077/ https://ncbi.nlm.nih.gov/pubmed/19057511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.238 |
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