Detection and Correlation of Single and Concomitant TP53, PTEN, and CDKN2A Alterations in Gliomas

Gliomas are the most frequent primary tumors of central nervous system and represent a heterogeneous group of tumors that originates from the glial cells. TP53, PTEN, and CDKN2A are important tumor suppressor genes that encode proteins involved in sustaining cellular homeostasis by different signali...

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Pubblicato in:Int J Mol Sci
Autori principali: Pessôa, Igor Andrade, Amorim, Carolina Koury, Ferreira, Wallax Augusto Silva, Sagica, Fernanda, Brito, José Reginaldo, Othman, Moneeb, Meyer, Britta, Liehr, Thomas, de Oliveira, Edivaldo Herculano C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6600458/
https://ncbi.nlm.nih.gov/pubmed/31151164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20112658
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