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Radiation-induced DNA damage cooperates with heterozygosity of TP53 and PTEN to generate high grade gliomas
Glioblastomas (GBM) are lethal brain tumors which are treated with conventional radiation (X-rays and gamma rays) or particle radiation (protons and carbon ions). Paradoxically, radiation is also a risk factor for GBM development, raising the possibility that radiotherapy of brain tumors could promo...
Shranjeno v:
| izdano v: | Cancer Res |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6635038/ https://ncbi.nlm.nih.gov/pubmed/31088835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0680 |
| Oznake: |
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