A High‐Affinity Calmodulin‐Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells

The molecular mechanisms and forces involved in the translocation of bacterial toxins into host cells are still a matter of intense research. The adenylate cyclase (CyaA) toxin from Bordetella pertussis displays a unique intoxication pathway in which its catalytic domain is directly translocated acr...

詳細記述

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書誌詳細
出版年:Adv Sci (Weinh)
主要な著者: Voegele, Alexis, Sadi, Mirko, O'Brien, Darragh Patrick, Gehan, Pauline, Raoux‐Barbot, Dorothée, Davi, Maryline, Hoos, Sylviane, Brûlé, Sébastien, Raynal, Bertrand, Weber, Patrick, Mechaly, Ariel, Haouz, Ahmed, Rodriguez, Nicolas, Vachette, Patrice, Durand, Dominique, Brier, Sébastien, Ladant, Daniel, Chenal, Alexandre
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2021
主題:
Full Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097335/
https://ncbi.nlm.nih.gov/pubmed/33977052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202003630
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