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Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region

The adenylate cyclase toxin CyaA is involved in the early stages of infection by Bordetella pertussis, the causative agent of whooping cough. CyaA intoxicates target cells by a direct translocation of its catalytic domain (AC) across the plasma membrane and produces supraphysiological levels of cAMP...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Voegele, Alexis, Subrini, Orso, Sapay, Nicolas, Ladant, Daniel, Chenal, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705984/
https://ncbi.nlm.nih.gov/pubmed/29135925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9110369
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