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The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro

The adenylate cyclase (CyaA) toxin produced in Bordetella pertussis is the causative agent of whooping cough. CyaA exhibits the remarkable capacity to translocate its N-terminal adenyl cyclase domain (ACD) directly across the plasma membrane into the cytosol of eukaryotic cells. Once translocated, c...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Voegele, Alexis, Sadi, Mirko, Raoux-Barbot, Dorothée, Douché, Thibaut, Matondo, Mariette, Ladant, Daniel, Chenal, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409671/
https://ncbi.nlm.nih.gov/pubmed/30781809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11020111
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