Llwytho...

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy

The adenylate cyclase toxin (CyaA) is one of the major virulence factors of Bordetella pertussis, the causative agent of whooping cough. CyaA is able to invade eukaryotic cells where, upon activation by endogenous calmodulin, it synthesizes massive amounts of cAMP that alters cellular physiology. Th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxins (Basel)
Prif Awduron: Chenal, Alexandre, Ladant, Daniel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070788/
https://ncbi.nlm.nih.gov/pubmed/30037010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10070302
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!