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Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin

Bordetella pertussis, the causative agent of whopping cough, produces an adenylate cyclase toxin (CyaA) that plays a key role in the host colonization by targeting innate immune cells which express CD11b/CD18, the cellular receptor of CyaA. CyaA is also able to invade non-phagocytic cells, via a uni...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Angely, Christelle, Ladant, Daniel, Planus, Emmanuelle, Louis, Bruno, Filoche, Marcel, Chenal, Alexandre, Isabey, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213728/
https://ncbi.nlm.nih.gov/pubmed/32392246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228606
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