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Bordetella pertussis adenylate cyclase toxin translocation across a tethered lipid bilayer

Numerous bacterial toxins can cross biological membranes to reach the cytosol of mammalian cells, where they exert their cytotoxic effects. Our model toxin, the adenylate cyclase (CyaA) from Bordetella pertussis, is able to invade eukaryotic cells by translocating its catalytic domain directly acros...

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Detalhes bibliográficos
Main Authors: Veneziano, Rémi, Rossi, Claire, Chenal, Alexandre, Devoisselle, Jean-Marie, Ladant, Daniel, Chopineau, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870713/
https://ncbi.nlm.nih.gov/pubmed/24297899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312975110
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