Endothelial IGF‐1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity

Changes in composition of the intestinal microbiota are linked to the development of obesity and can lead to endothelial cell (EC) dysfunction. It is unknown whether EC can directly influence the microbiota. Insulin‐like growth factor‐1 (IGF‐1) and its receptor (IGF‐1R) are critical for coupling nut...

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Publicat a:EMBO Rep
Autors principals: Haywood, Natalie J, Luk, Cheukyau, Bridge, Katherine I, Drozd, Michael, Makava, Natallia, Skromna, Anna, Maccannell, Amanda, Ozber, Claire H, Warmke, Nele, Wilkinson, Chloe G, Watt, Nicole T, Koch‐Paszkowski, Joanna, Teh, Irvin, Boyle, Jordan H, Smart, Sean, Schneider, Jurgen E, Yuldasheva, Nadira Y, Roberts, Lee D, Beech, David J, Sukumar, Piruthivi, Wheatcroft, Stephen B, Cubbon, Richard M, Kearney, Mark T
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
Matèries:
Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097321/
https://ncbi.nlm.nih.gov/pubmed/33934497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050767
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