Endothelial IGF‐1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity

Changes in composition of the intestinal microbiota are linked to the development of obesity and can lead to endothelial cell (EC) dysfunction. It is unknown whether EC can directly influence the microbiota. Insulin‐like growth factor‐1 (IGF‐1) and its receptor (IGF‐1R) are critical for coupling nut...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Haywood, Natalie J, Luk, Cheukyau, Bridge, Katherine I, Drozd, Michael, Makava, Natallia, Skromna, Anna, Maccannell, Amanda, Ozber, Claire H, Warmke, Nele, Wilkinson, Chloe G, Watt, Nicole T, Koch‐Paszkowski, Joanna, Teh, Irvin, Boyle, Jordan H, Smart, Sean, Schneider, Jurgen E, Yuldasheva, Nadira Y, Roberts, Lee D, Beech, David J, Sukumar, Piruthivi, Wheatcroft, Stephen B, Cubbon, Richard M, Kearney, Mark T
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097321/
https://ncbi.nlm.nih.gov/pubmed/33934497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050767
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