Does inorganic nitrate say NO to obesity by browning white adipose tissue?

Por Roberts, Lee D
Publicado no Adipocyte (2015)

Towards New Biomarkers of Cardiometabolic Diseases

Por Roberts, Lee D., Gerszten, Robert E.
Publicado em 2013

Dietary inorganic nitrate: From villain to hero in metabolic disease?

Por McNally, Ben, Griffin, Julian L., Roberts, Lee D.
Publicado no Mol Nutr Food Res (2015)

Targeted Metabolomics

Por Roberts, Lee D., Souza, Amanda L., Gerszten, Robert E., Clish, Clary B.
Publicado em 2012

A role for vaccinia virus protein C16 in reprogramming cellular energy metabolism

Por Mazzon, Michela, Castro, Cecilia, Roberts, Lee D., Griffin, Julian L., Smith, Geoffrey L.
Publicado no J Gen Virol (2015)

Metabolic phenotyping of a model of adipocyte differentiation

Por Roberts, Lee D., Virtue, Sam, Vidal-Puig, Antonio, Nicholls, Andrew W., Griffin, Julian L.
Publicado em 2009

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue

Por Roberts, Lee D, Murray, Andrew J, Menassa, David, Ashmore, Tom, Nicholls, Andrew W, Griffin, Julian L
Publicado em 2011

Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor δ from Peroxisome proliferator-activated receptor γ in the ob/ob mouse...

Por Roberts, Lee D, Hassall, David G, Winegar, Deborah A, Haselden, John N, Nicholls, Andrew W, Griffin, Julian L
Publicado em 2009

PTPMT1 Inhibition Lowers Glucose Through Phosphorylation of SDH

Por Nath, Anjali K., Ryu, Justine H., Jin, Youngnam N., Roberts, Lee D., Dejam, Andre, Gerszten, Robert E., Peterson, Randall T.
Publicado no Cell Rep (2015)

PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling

Por Ament, Zsuzsanna, West, James A., Stanley, Elizabeth, Ashmore, Tom, Roberts, Lee D., Wright, Jayne, Nicholls, Andrew W., Griffin, Julian L.
Publicado no Free Radic Biol Med (2016)

Inorganic Nitrate Promotes the Browning of White Adipose Tissue through the Nitrate-Nitrite-Nitric Oxide Pathway

Por Roberts, Lee D, Ashmore, Tom, Kotwica, Aleksandra O, Murfitt, Steven A, Fernandez, Bernadette O, Feelisch, Martin, Murray, Andrew J, Griffin, Julian L
Publicado no Diabetes (2014)

Metabolomics dataset of PPAR-pan treated rat liver

Por Ament, Zsuzsanna, West, James A., Stanley, Elizabeth, Li, Xuefei, Ashmore, Tom, Roberts, Lee D., Wright, Jayne, Nicholls, Andrew W., Griffin, Julian L.
Publicado no Data Brief (2016)

Erratum: Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance

Por Tan, Chong Yew, Virtue, Samuel, Murfitt, Steven, Roberts, Lee D., Phua, Yi Hui, Dale, Martin, Griffin, Julian L., Tinahones, Francisco, Scherer, Philipp E., Vidal-Puig, Antonio
Publicado no Sci Rep (2016)

An In Vivo Zebrafish Screen Identifies Organophosphate Antidotes with Diverse Mechanisms of Action

Por Jin, Shan, Sarkar, Kumar S., Jin, Youngnam N., Liu, Yan, Kokel, David, Van Ham, Tjakko J., Roberts, Lee D., Gerszten, Robert E., MacRae, Calum A., Peterson, Randall T.
Publicado em 2012

Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes

Por Eiden, Michael, Koulman, Albert, Hatunic, Mensud, West, James A., Murfitt, Steven, Osei, Michael, Adams, Claire, Wang, Xinzhu, Chu, Yajing, Marney, Luke, Roberts, Lee D., O’Rahilly, Stephen, Semple, Robert K., Savage, David B., Griffin, Julian L.
Publicado no Genome Med (2015)

Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure

Por Nath, Anjali K., Roberts, Lee D., Liu, Yan, Mahon, Sari B., Kim, Sonia, Ryu, Justine H., Werdich, Andreas, Januzzi, James L., Boss, Gerry R., Rockwood, Gary A., MacRae, Calum A., Brenner, Matthew, Gerszten, Robert E., Peterson, Randall T.
Publicado em 2013

Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism

Por Ashmore, Tom, Roberts, Lee D., Morash, Andrea J., Kotwica, Aleksandra O., Finnerty, John, West, James A., Murfitt, Steven A., Fernandez, Bernadette O., Branco, Cristina, Cowburn, Andrew S., Clarke, Kieran, Johnson, Randall S., Feelisch, Martin, Griffin, Julian L., Murray, Andrew J.
Publicado no BMC Biol (2015)

Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption

Por Sanders, Francis W. B., Acharjee, Animesh, Walker, Celia, Marney, Luke, Roberts, Lee D., Imamura, Fumiaki, Jenkins, Benjamin, Case, Jack, Ray, Sumantra, Virtue, Samuel, Vidal-Puig, Antonio, Kuh, Diana, Hardy, Rebecca, Allison, Michael, Forouhi, Nita, Murray, Andrew J., Wareham, Nick, Vacca, Michele, Koulman, Albert, Griffin, Julian L.
Publicado no Genome Biol (2018)

A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway

Por Sng, Christopher C.T., O'Byrne, Sorcha, Prigozhin, Daniil M., Bauer, Matthias R., Harvey, Jennifer C., Ruhle, Michelle, Challis, Ben G., Lear, Sara, Roberts, Lee D., Workman, Sarita, Janowitz, Tobias, Magiera, Lukasz, Doffinger, Rainer, Buckland, Matthew S., Jodrell, Duncan J., Semple, Robert K., Wilson, Timothy J., Modis, Yorgo, Thaventhiran, James E.D.
Publicado no J Allergy Clin Immunol (2018)

Metabolite Profiling Identifies Pathways Associated with Metabolic Risk in Humans

Por Cheng, Susan, Rhee, Eugene P., Larson, Martin G., Lewis, Gregory D., McCabe, Elizabeth L., Shen, Dongxiao, Palma, Melinda J., Roberts, Lee D., Dejam, Andre, Souza, Amanda L., Deik, Amy A., Magnusson, Martin, Fox, Caroline S., O'Donnell, Christopher J., Vasan, Ramachandran S., Melander, Olle, Clish, Clary B., Gerszten, Robert E., Wang, Thomas J.
Publicado em 2012