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Periplocin and cardiac glycosides suppress the unfolded protein response

The unfolded protein response (UPR) controls protein homeostasis through transcriptional and translational regulation. However, dysregulated UPR signaling has been associated with the pathogenesis of many human diseases. Therefore, the compounds modulating UPR may provide molecular insights for thes...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Tokugawa, Muneshige, Inoue, Yasumichi, Ishiuchi, Kan’ichiro, Kujirai, Chisane, Matsuno, Michiyo, Ri, Masaki, Itoh, Yuka, Miyajima, Chiharu, Morishita, Daisuke, Ohoka, Nobumichi, Iida, Shinsuke, Mizukami, Hajime, Makino, Toshiaki, Hayashi, Hidetoshi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097017/
https://ncbi.nlm.nih.gov/pubmed/33947921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89074-x
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