Periplocin and cardiac glycosides suppress the unfolded protein response

The unfolded protein response (UPR) controls protein homeostasis through transcriptional and translational regulation. However, dysregulated UPR signaling has been associated with the pathogenesis of many human diseases. Therefore, the compounds modulating UPR may provide molecular insights for thes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tokugawa, Muneshige, Inoue, Yasumichi, Ishiuchi, Kan’ichiro, Kujirai, Chisane, Matsuno, Michiyo, Ri, Masaki, Itoh, Yuka, Miyajima, Chiharu, Morishita, Daisuke, Ohoka, Nobumichi, Iida, Shinsuke, Mizukami, Hajime, Makino, Toshiaki, Hayashi, Hidetoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097017/
https://ncbi.nlm.nih.gov/pubmed/33947921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89074-x
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