3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders.

Neurodevelopmental disorders are thought to arise from interrupted development of the brain at an early age. Genome-wide association studies (GWAS) have identified hundreds of loci associated with susceptibility to neurodevelopmental disorders; however, which noncoding variants regulate which genes...

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Detalhes bibliográficos
Publicado no:Prog Neurobiol
Main Authors: Su, Chun, Argenziano, Mariana, Lu, Sumei, Pippin, James A., Pahl, Matthew C., Leonard, Michelle E., Cousminer, Diana L., Johnson, Matthew E., Lasconi, Chiara, Wells, Andrew D., Chesi, Alessandra, Grant, Struan F.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096691/
https://ncbi.nlm.nih.gov/pubmed/33545232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2021.102000
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