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Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

The restricted availability of suitable in vitro models that can reliably represent complex human brain development is a significant bottleneck that limits the translation of basic brain research into clinical application. While induced pluripotent stem cells (iPSCs) have replaced the ethically ques...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Gabriel, Elke, Gopalakrishnan, Jay
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564693/
https://ncbi.nlm.nih.gov/pubmed/28448044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55372
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