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Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

The restricted availability of suitable in vitro models that can reliably represent complex human brain development is a significant bottleneck that limits the translation of basic brain research into clinical application. While induced pluripotent stem cells (iPSCs) have replaced the ethically ques...

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Bibliografski detalji
Izdano u:J Vis Exp
Glavni autori: Gabriel, Elke, Gopalakrishnan, Jay
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564693/
https://ncbi.nlm.nih.gov/pubmed/28448044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55372
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