Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease

BACKGROUND & AIMS: Inflammatory bowel disease (IBD) is a polygenic disorder characterized principally by dysregulated inflammation impacting the gastrointestinal tract. However, there also is increasing evidence for a clinical association with stress and depression. Given the role of the hypotha...

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Dades bibliogràfiques
Publicat a:Cell Mol Gastroenterol Hepatol
Autors principals: Lasconi, Chiara, Pahl, Matthew C., Cousminer, Diana L., Doege, Claudia A., Chesi, Alessandra, Hodge, Kenyaita M., Leonard, Michelle E., Lu, Sumei, Johnson, Matthew E., Su, Chun, Hammond, Reza K., Pippin, James A., Terry, Natalie A., Ghanem, Louis R., Leibel, Rudolph L., Wells, Andrew D., Grant, Struan F.A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843407/
https://ncbi.nlm.nih.gov/pubmed/33069917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.10.004
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