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Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density
Osteoporosis is a devastating disease with an essential genetic component. GWAS have discovered genetic signals robustly associated with bone mineral density (BMD), but not the precise localization of effector genes. Here, we carry out physical and direct variant to gene mapping in human mesenchymal...
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| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6425012/ https://ncbi.nlm.nih.gov/pubmed/30890710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09302-x |
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