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Mechanisms of substrate recognition by the 26S proteasome

The majority of regulated protein degradation in eukaryotes is accomplished by the 26S proteasome, the large proteolytic complex responsible for removing regulatory proteins and damaged proteins. Proteins are targeted to the proteasome by ubiquitination, and degradation is initiated at a disordered...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Struct Biol
Main Authors: Davis, Caroline, Spaller, Brian Logan, Matouschek, Andreas
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096638/
https://ncbi.nlm.nih.gov/pubmed/33296738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.10.010
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