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An assay for 26S proteasome activity based on fluorescence anisotropy measurements of dye-labeled protein substrates
The 26S proteasome is the molecular machine at the center of the ubiquitin–proteasome system and is responsible for adjusting the concentrations of many cellular proteins. It is a drug target in several human diseases, and assays for the characterization of modulators of its activity are valuable. T...
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| Publié dans: | Anal Biochem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976823/ https://ncbi.nlm.nih.gov/pubmed/27296635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2016.05.026 |
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