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Mechanisms of substrate recognition by the 26S proteasome

The majority of regulated protein degradation in eukaryotes is accomplished by the 26S proteasome, the large proteolytic complex responsible for removing regulatory proteins and damaged proteins. Proteins are targeted to the proteasome by ubiquitination, and degradation is initiated at a disordered...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Davis, Caroline, Spaller, Brian Logan, Matouschek, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096638/
https://ncbi.nlm.nih.gov/pubmed/33296738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.10.010
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