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Mechanisms of substrate recognition by the 26S proteasome
The majority of regulated protein degradation in eukaryotes is accomplished by the 26S proteasome, the large proteolytic complex responsible for removing regulatory proteins and damaged proteins. Proteins are targeted to the proteasome by ubiquitination, and degradation is initiated at a disordered...
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| Publicado en: | Curr Opin Struct Biol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8096638/ https://ncbi.nlm.nih.gov/pubmed/33296738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.10.010 |
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