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Mechanisms of substrate recognition by the 26S proteasome
The majority of regulated protein degradation in eukaryotes is accomplished by the 26S proteasome, the large proteolytic complex responsible for removing regulatory proteins and damaged proteins. Proteins are targeted to the proteasome by ubiquitination, and degradation is initiated at a disordered...
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| 發表在: | Curr Opin Struct Biol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8096638/ https://ncbi.nlm.nih.gov/pubmed/33296738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.10.010 |
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