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CRISPR/Cas9-Constructed Pseudorabies Virus Mutants Reveal the Importance of UL13 in Alphaherpesvirus Escape from Genome Silencing

Latent and recurrent productive infection of long-living cells, such as neurons, enables alphaherpesviruses to persist in their host populations. Still, the viral factors involved in these events remain largely obscure. Using a complementation assay in compartmented primary peripheral nervous system...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Van Cleemput, Jolien, Koyuncu, Orkide O., Laval, Kathlyn, Engel, Esteban A., Enquist, Lynn W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094956/
https://ncbi.nlm.nih.gov/pubmed/33361431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02286-20
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