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Alphaherpesvirus infection of mice primes PNS neurons to an inflammatory state regulated by TLR2 and type I IFN signaling

Pseudorabies virus (PRV), an alphaherpesvirus closely related to Varicella-Zoster virus (VZV) and Herpes simplex type 1 (HSV1) infects mucosa epithelia and the peripheral nervous system (PNS) of its host. We previously demonstrated that PRV infection induces a specific and lethal inflammatory respon...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Laval, Kathlyn, Van Cleemput, Jolien, Vernejoul, Jonah B., Enquist, Lynn W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824567/
https://ncbi.nlm.nih.gov/pubmed/31675371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008087
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