CRISPR/Cas9-Constructed Pseudorabies Virus Mutants Reveal the Importance of UL13 in Alphaherpesvirus Escape from Genome Silencing

Latent and recurrent productive infection of long-living cells, such as neurons, enables alphaherpesviruses to persist in their host populations. Still, the viral factors involved in these events remain largely obscure. Using a complementation assay in compartmented primary peripheral nervous system...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Van Cleemput, Jolien, Koyuncu, Orkide O., Laval, Kathlyn, Engel, Esteban A., Enquist, Lynn W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094956/
https://ncbi.nlm.nih.gov/pubmed/33361431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02286-20
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