A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vivo Activity in a Murine Model of Hematogenously Disseminated Candida albicans

Echinocandins are a first-line therapy for Candida infections through their ability to inhibit the synthesis of polymer β-(1,3)-d-glucan. However, there has been an emergence of multidrug-resistant fungal species necessitating the development of novel antifungal agents to combat invasive fungal infe...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Chu, Sherman, Long, Lisa, McCormick, Thomas S., Borroto-Esoda, Katyna, Barat, Stephen, Ghannoum, Mahmoud A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092520/
https://ncbi.nlm.nih.gov/pubmed/33318003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01989-20
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