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A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vitro Activity against Candida auris and Other Clinically Relevant Fungal Isolates

Due to the increase of antifungal drug resistance and difficulties associated with drug administration, new antifungal agents for invasive fungal infections are needed. SCY-247 is a second-generation fungerp antifungal compound that interferes with the synthesis of the fungal cell wall polymer β-(1,...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Chu, Sherman, Long, Lisa, Sherif, Rania, McCormick, Thomas S., Borroto-Esoda, Katyna, Barat, Stephen, Ghannoum, Mahmoud A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092514/
https://ncbi.nlm.nih.gov/pubmed/33317999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01988-20
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