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A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vitro Activity against Candida auris and Other Clinically Relevant Fungal Isolates

Due to the increase of antifungal drug resistance and difficulties associated with drug administration, new antifungal agents for invasive fungal infections are needed. SCY-247 is a second-generation fungerp antifungal compound that interferes with the synthesis of the fungal cell wall polymer β-(1,...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Chu, Sherman, Long, Lisa, Sherif, Rania, McCormick, Thomas S., Borroto-Esoda, Katyna, Barat, Stephen, Ghannoum, Mahmoud A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092514/
https://ncbi.nlm.nih.gov/pubmed/33317999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01988-20
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