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A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vitro Activity against Candida auris and Other Clinically Relevant Fungal Isolates

Due to the increase of antifungal drug resistance and difficulties associated with drug administration, new antifungal agents for invasive fungal infections are needed. SCY-247 is a second-generation fungerp antifungal compound that interferes with the synthesis of the fungal cell wall polymer β-(1,...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Chu, Sherman, Long, Lisa, Sherif, Rania, McCormick, Thomas S., Borroto-Esoda, Katyna, Barat, Stephen, Ghannoum, Mahmoud A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092514/
https://ncbi.nlm.nih.gov/pubmed/33317999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01988-20
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