PIP(2) corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity

Cerebral small vessel diseases (SVDs) are a central link between stroke and dementia—two comorbidities without specific treatments. Despite the emerging consensus that SVDs are initiated in the endothelium, the early mechanisms remain largely unknown. Deficits in on-demand delivery of blood to activ...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Dabertrand, Fabrice, Harraz, Osama F., Koide, Masayo, Longden, Thomas A., Rosehart, Amanda C., Hill-Eubanks, David C., Joutel, Anne, Nelson, Mark T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2021
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092380/
https://ncbi.nlm.nih.gov/pubmed/33875602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025998118
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