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PIP(2): A critical regulator of vascular ion channels hiding in plain sight
The phosphoinositide, phosphatidylinositol 4,5-bisphosphate (PIP(2)), has long been established as a major contributor to intracellular signaling, primarily by virtue of its role as a substrate for phospholipase C (PLC). Signaling by G(q)-protein–coupled receptors triggers PLC-mediated hydrolysis of...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7456132/ https://ncbi.nlm.nih.gov/pubmed/32764146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006737117 |
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