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Capillary K(+)-sensing initiates retrograde hyperpolarization to locally increase cerebral blood flow

Blood flow into the brain is dynamically regulated to satisfy the changing metabolic requirements of neurons, but how this is accomplished has remained unclear. Here, we demonstrate a central role for capillary endothelial cells in sensing neural activity and communicating it to upstream arterioles...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Neurosci
Egile Nagusiak: Longden, Thomas A., Dabertrand, Fabrice, Koide, Masayo, Gonzales, Albert L., Tykocki, Nathan R., Brayden, Joseph E., Hill-Eubanks, David, Nelson, Mark T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404963/
https://ncbi.nlm.nih.gov/pubmed/28319610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4533
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