Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner

Human immunodeficiency virus type 1 (HIV-1) capsid binds host proteins during infection, including cleavage and polyadenylation specificity factor 6 (CPSF6) and cyclophilin A (CypA). We observe that HIV-1 infection induces higher-order CPSF6 formation, and capsid-CPSF6 complexes cotraffic on microtu...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:mBio
Main Authors: Zhong, Zhou, Ning, Jiying, Boggs, Emerson A., Jang, Sooin, Wallace, Callen, Telmer, Cheryl, Bruchez, Marcel P., Ahn, Jinwoo, Engelman, Alan N., Zhang, Peijun, Watkins, Simon C., Ambrose, Zandrea
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092277/
https://ncbi.nlm.nih.gov/pubmed/33758083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03142-20
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki