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Intrinsic curvature of HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A
The mature retrovirus capsid consists of a variably curved lattice of capsid protein (CA) hexamers and pentamers. High-resolution structures of the curved assembly, or in complex with host factors, have not been available. By devising new cryoEM methodologies for exceedingly flexible and pleomorphic...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Struct Mol Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8064030/ https://ncbi.nlm.nih.gov/pubmed/32747784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0467-8 |
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