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Capsid-CPSF6 interaction licenses nuclear HIV-1 trafficking to sites of viral DNA integration
HIV-1 integration into the host genome favors actively transcribed genes. Prior work indicated that the nuclear periphery provides the architectural basis for integration site selection, with viral capsid-binding host cofactor CPSF6 and viral integrase-binding cofactor LEDGF/p75 contributing to sele...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Cell Host Microbe |
|---|---|
| Prif Awduron: | , , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368089/ https://ncbi.nlm.nih.gov/pubmed/30173955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.08.002 |
| Tagiau: |
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