The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b

Cleavage and polyadenylation specificity factor 6 (CPSF6) is a cellular protein involved in mRNA processing. Emerging evidence suggests that CPSF6 also plays key roles in HIV-1 infection, specifically during nuclear import and integration targeting. However, the cellular and molecular mechanisms tha...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Chaudhuri, Evan, Dash, Sabyasachi, Balasubramaniam, Muthukumar, Padron, Adrian, Holland, Joseph, Sowd, Gregory A., Villalta, Fernando, Engelman, Alan N., Pandhare, Jui, Dash, Chandravanu
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2020
Предметы:
Gene Regulation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152771/
https://ncbi.nlm.nih.gov/pubmed/32152226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010534
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